Portfolio

The MCRN has established twelve Clinical Studies Groups (CSG’s) covering the majority of paediatric specialties, listed below with their main contacts:

•    Allergy, Nephrology, Infection, Immunity and Haematology - Dr Mike Sharland, St. George’s Hospital
•    Anaesthesia, Intensive Care, Pain Control and Cardiology - Dr Robert Tasker, Cambridge
•    Diabetes, Endocrinology and Metabolic Medicine - Professor David Dunger, Cambridge
•    Gastroenterology, Hepatology and Nutrition - Dr Stephen Murphy, Birmingham
•    General Paediatrics - Dr Colin Powell, Cardiff
•    Neonatal - Professor David Field, Leicester
•    Neurosciences - Dr William Whitehouse, Nottingham
•    Methodology - Peter Brocklehurst, Oxford
•    Pharmacy and Pharmacology (including Paediatric Formulations and Pharmacokinetics) - Professor James McElnay, London
•    Respiratory and Cystic Fibrosis - Prof. Jonathan Grigg, London
•    Rheumatology (arc/MCRN collaboration) - Dr Mike Sharland, St. George’s Hospital
•    Children’s Cancer and Leukaemia Group (CCLG; please note that this is a Specialist Research Network within the National Cancer Research Network; NCRN)

CSG’s identify gaps and priorities in research, and develop study proposals to address important clinical questions that are relevant to children. All the specialties are covered by the TLCRN; therefore, if there’s not one already, there should be a study in your specialty soon.

The UKCRN has introduced the following performance management targets, which will apply to our portfolio:

•    The development of a balanced portfolio of commercial and non-commercial clinical studies, as assessed by an international review panel.
•    The speed of set up and final recruitment. The first subject that is recruited at a site should be recruited within four weeks of final site approval. The date of the recruitment of the last subject will be compared with the planned close of recruitment.
•    The accrual of subjects into studies. 80% of studies should achieve their accrual target by the planned close of recruitment.

Add something here about feasibility studies …

The Trent Local Children’s Research Network operates as part of the NIHR Medicines for Children Research Network in England. It is part of the National Institute for Health Research and forms part of the UK Clinical Research Network. The Networks support and deliver high quality clinical research studies.
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